http://ir.haramaya.edu.et//hru/handle/123456789/106 2026-06-02T18:48:45Z http://ir.haramaya.edu.et//hru/handle/123456789/8473 MAGNITUDE OF ADVERSE FETAL OUTCOMES AND ASSOCIATED FACTORS AMONG WOMEN WITH PREMATURE RUPTURE OF MEMBRANE WHO GAVE BIRTH AT PUBLIC HOSPITALS IN HARARI REGION, EASTERN ETHIOPIA Naol Oda; Dr. Kasiye Shiferaw; Dr. Kasiye Shiferaw Premature rupture of membranes is a common occurrence in many pregnancies, resulting in adverse fetal outcomes that range from mild to irreversible long-term neonatal complications and even death. However, there is a lack of information concerning adverse fetal outcomes among women who have experienced premature rupture of membranes in the study area. Objective: This study aimed to identify the magnitude of adverse fetal outcomes and the factors associated with premature rupture of the membrane among women who gave birth at public hospitals in Harari Region, Eastern Ethiopia, from January 1, 2021, to December 31, 2023. Methods: A hospital-based cross-sectional study design was conducted from September 1 to 15, 2024. A simple random sampling technique was employed to select 421 charts of women diagnosed with premature rupture of membranes who gave birth at public hospitals in the Harari region. Data were collected using a data extraction checklist through Kobo Toolbox software. The collected data were exported and analyzed using Stata version 17. Descriptive analyses included percentages, frequency distributions, and measures of central tendency like the mean. A binary logistic regression model was then utilized to determine the association between independent and dependent variables. Adjusted odds ratios with 95% confidence intervals were used to measure the strength of the association. A P-value of ≤ 0.05 was used to declare statistical significance. Results: The magnitude of adverse fetal outcomes among women who experienced premature rupture of membranes was 35.9% [95% CI, 31.3 to 40.7]. Factors significantly associated with adverse fetal outcomes included being rural residents [AOR=1.96, 95% CI (1.14-3.36)], preterm birth [AOR=6.48, 95% CI (3.45-12.15)], anemia during pregnancy [AOR=2.9, 95% CI (1.69- 4.96)], and a history of adverse fetal outcomes [AOR=4.55, 95% CI (2.40-8.65)]. The magnitude of adverse fetal outcomes in this study was significant. Rural residents, preterm birth, anemia, and a history of adverse fetal outcomes were significantly associated with these outcomes. The findings highlighted improvements in maternal healthcare access, especially in rural areas, early detection of anemia and iron supplementation, and the optimization of preconception care for mothers with a history of adverse fetal outcomes. 56p. 2025-03-01T00:00:00Z http://ir.haramaya.edu.et//hru/handle/123456789/8469 Adverse Maternal and Perinatal Outcomes and Its Associated Factors Among Women Admitted with Hhypertensive Ddisorders of pregnancy in public hospitals in Harari Regional State Ethiopia. Mohammed Damtew Ali; Dr. Haymanot Mezmur; Dr. Agumasie Semahegn Hypertensive disorders of pregnancy remain a major global health issue because of the area of significant public health concern due to associated maternal and perinatal morbidity and mortality. There is information on maternal and perinatal adverse outcomes of hypertensive disorders of pregnancy in Eastern Ethiopia. Objective: The objective of this study was to assess the magnitude of, adverse maternal and perinatal outcomes and its associated factors of hypertensive disorders in pregnancy women who admitted and delivered at selected health facilities in Harar Ethiopia from August 1/2018 to July 31/2023 during the data collection period from August 26/2023 to September 22/2023. Methods: A retrospective cross-sectional study was conducted among randomly selected 703 from 4683 women who admitted to public hospitals and attended delivery in Harar Ethiopia. Data were abstracted by using structured checklist. Data was entered and cleaned using Epi Data 4.6 and then exported to Stata software version 17 for analysis. Bivariate and multivariable logistic regression models were used. Adjusted odd ratio, 95% confidence interval, and p value <0.05 was used to identify associated with adverse maternal and perinatal outcome. Result: The overall prevalence of adverse maternal outcomes was 44.81% (95% CI: 41.08%- 48.57%) and the overall prevalence of adverse perinatal outcomes was 58.18% (95% CI: 54.43%- 61.85%). Having no of ANC follow up (AOR: 1.21- 2.44), primigravida (AOR: 1.44 95%CI: 1.05- 1.96), referrals on arrived (AOR:1.68, 95% CI: 1.13 – 2.50), and having history of medical disease (AOR: 1.91, 95% CI: 1.28 - 2.83) was significantly associated with adverse maternal outcome Maternal age less than 20 years, rural residence, gestational age less than 34 weeks, and mother having eclampsia was significantly associated with adverse perinatal outcome. Conclusions: In this study, the prevalence of adverse perinatal and maternal outcomes was relatively high. ANC follow up, gravidity, referrals on arrival, and having medical history was significantly associated with adverse maternal outcome. Whereas maternal age, maternal residence, gestational age, and mother having eclampsia was significantly associated with adverse perinatal outcome 68p. 2025-04-01T00:00:00Z http://ir.haramaya.edu.et//hru/handle/123456789/8284 SURVIVAL STATUS AND PREDICTORS OF MORTALITY AMONG LOW-BIRTH-WEIGHT NEONATES ADMITTED TO NEONATAL INTENSIVE CARE UNITS IN SELECTED PUBLIC HOSPITALS OF DIRE DAWA CITY ADMINSTRATION AND HARARI REGIONAL STATE , EASTERN ETHIOPIA, 2024. Mekonine Tegenegn (BSC); Mr Teshale Mulatu(MSc, Assistant Professor); Mr Yohannes Baye (MSc, Assistant Professor) Background: Low-Birth-Weight is a serious public health concern in low- and middle-income countries. Globally, more than 20.5 million neonates were born as low-birth-weight and more than 96% of these Low-Birth-Weight newborns are born in developing countries. Although the World Health Assembly targeted to reduce Low-Birth-Weight by 30% by the end of 2025, a little success has been achieved in Ethiopia. Objective: To assess the survival status and predictors of neonatal mortality among low birth weight neonates admitted to neonatal intensive care units in public hospitals of Dire Dawa city administration and Harari regional state, eastern Ethiopia, in 2023. Methods: An institution-based retrospective follow-up study was conducted among 560 low birth-weight neonates admitted to the neonatal intensive care unit, by reviewing chart from January1, 2020-December 30, 2022.proportional allocation to sample size was made for each hospital and then simple random sampling by computer generating method was used to select neonatal charts. A checklist was used to extract pertinent information. Epi-data version 4.6 was used for data entry, and then exported to Stata14 software for analysis. To estimate the cumulative survival time and compare the probability of survival time among variables, the Kaplan-Meier survival curve, and the Log-rank test was used. Bivariable and multivariable Cox proportional hazard model was used to identify predictor variables. Model goodness-of-fit was checked by Cox Snell residuals & an assumption was checked by using Schoenfeld residual test. Results: The overall incidence density was 67.85 per 1000 person-day observations (95%CI: 59.15, 78.21) with 2932 person-days observation and median survival time of 12 days. Being born from a mother living outside the city (rural resident) [AHR= 1.5(1.05, 1.99)]. Unable to breast feeding [2.3(AHR: 2.3 (95%, CI: 1.38, 2.79)], lack of Kangaroo-Mather Care [AHR: 1.6 (95%, CI: 1.015, 2.43)], neonatal sepsis [(AHR: 1.6 (95% CI: (1.15,2.25)], Perinatal asphyxia [AHR:2.2(95% CI:1.48,1.15)], and Necrotizing Enter colitis [AHR:2.7 (95% CI:1.53, 1.70)] were found to be significant predictors of death among low-birth-weight. Conclusion and recommendation: The incidence rate of LBW neonatal mortality was high and continues as a public health issue. The median survival time of the neonate was 12 days. Therefore, an intervention that focuses on the identified predictors could have a paramount effect in reducing low birth weight neonatal death. 68 2024-07-01T00:00:00Z http://ir.haramaya.edu.et//hru/handle/123456789/8055 PREGNANCY OUTCOME AMONG WOMEN WITH OLIGOHYDRAMNIOS AT TERM IN TWO TEACHING HOSPITALS IN HARAR, ETHIOPIA DR. SEMIR SULTAN (OBGYN SPECIALIST, MATERNAL FETAL MEDICINE FELLOW); YeshiwasSewagegn(Maternal Fetal Medicine Subspecialist); Abera Kenay(PhD): Background: Oligohydramnios is defined in clinical practice as amniotic fluid index of less than 5 cm or single deepest pocket of less than 2cm when measured by ultrasound. As there is no clear national or institutional guideline addressing oligohydramnios, women with oligohydramnios are managed differently in the different hospitals.Although it is a frequently occurring condition in pregnant women managed in the two teaching hospitals in Harar, Ethiopia, there are no studies done so far to assess its impact on maternal and neonatal outcomes in these setups. The information generated by study serves as a baseline. Objective: To assess the pregnancy outcome among women with oligohydramnios at term in two teaching Hospitals in Harar, Ethiopia from 1st of January 2022 to 31th of December 2023. Data was collected from May 1st to 30th, 2024. Methodology: Institutions based retrospective cross-sectional study was done at the teaching hospitals in Harar. Two hundred eleven women with oligohydramnios at term having singleton fetus presenting to the outpatient departments was included using whole population sampling. These women were followed for their pregnancy outcomes till discharge from the hospitals. The association between variables was done using chi square, Kruskal Wallis test, t test/One way ANOVA, and logistic regression analysis Result: There were 211 (2.1%) women, whose pregnancies were complicated with oligohydrmnios at or beyond 37 weeks of gestation among 9910 deliveries at the two hospitals during the study period from the 1st of January 2022 to 31th of Dec, 2023. Over all cesearen rate was 144(68.2%). Among those women who had trial of labor, the c/s rate was 54(44.6%). The gross perinatal mortality rate and corrected perinatal mortality rate in this study were 52.1 in 1000 and 35.2 per 1000 deliveries respectively Conclusions: Oligohydramnios at term was a common condition in the teaching hospitals. Women with oligohydramnios had high neonatal morbidities and mortalits. Women with oligohydramnios had also high caesarean section deliveries. 68 2024-07-01T00:00:00Z