Abstract:
The present work was carried out to synthesize the title compounds by using two different
Amberlite catalysts viz. Amberlite IRA 67 and Amberlite IRC 86. The title compounds were
synthesized in good yields under both catalysts. The structures of the as-synthesized compound
were identified using IR and one dimensional NMR techniques such as 1H NMR, 13C NMR and
DEPT-135. Comparison between the two catalysts with respect to percentage yield, reaction time,
facile work up procedures and catalyst recovery evidenced Amberlite IRA 67 as better catalyst
than Amberlite IRC 86. The synthesized compounds were tested against four bacterial species (two
gram negative and two gram positive bacteria) and two fungal species (Fusarium oxysporum and
Aspergillus niger) using paper disc diffusion method. Based on the findings of the present work out
of the four bacteria species considered in this study, relatively good inhibition zone was evidenced
for the three of them while Streptococcus agalactia doesn't show any inhibition zone. On the other
hand, of the two fungal species Fusarium oxysporum was inhibited by the as-synthesized
compound where as Aspergillus niger doesn't show any inhibition zone.
