PREVALENCE AND ANTIBIOTIC SUSCEPTIBILITY OF BACTERIAL UROPATHOGENS AMONG PATIENTS OF URINARY TRACT INFECTION

Abstract

Urinary tract infection is one of the most prevalent infections caused by different pathogens. This study was designed to determine the prevalence and antimicrobial susceptibility patterns of uropathogens among patients visiting Hasasa Health Center from March to May 2016.A total of 384 patients participated in this study. Culturing and identification of uropathogens were performed by using agar (Mac-Conkey agar and blood agar) and biochemical test. Antimicrobial resistance testing was performed by the Kerby Bauer disk diffusion method. Forty-four (44) uropathogens were isolated from urine samples of the 384-suspected patients with 11.5%overall prevalence of all isolates. The prevalence of Urinary Tract Infectionin female and male was 35(79.5%), 9(20.5% respectively. The highest prevalence of Urinary Tract Infectionis for the age range of 19-28 (17.4%) followed by 29-38(11.8%), 9-18(8.3%), 39-48(7.5%), and more than 49 (5.8%), respectively. Escherichia coli were the most prevalent isolates (56.8%) among the isolates in this study. The other isolates were Proteus mirabilis, Klebisiellapnemoniae, Enterococcus spp, and Enterobactersppwith respective prevalence of 22.7 %, 13.6%, 4.6%, and 2.3%. The highest resistance of isolates was observed toamoxicillin(88.6%)and lowest résistance was to nitrofurantoin (27.3%).All isolates showed high sensitivity to nitrofurantoin (72.7%)and lowest sensitivity to amoxicillin (11.4%). Over the last ten years (2005 to 2014)in the study area, Urinary Tract Infectionprevalence shows a decreasing condition.In conclusion, the present study showed that,lower overall prevalence of Urinary Tract Infectionthan most of the study conducted in other areas. So all stakeholder in the study area can participate in prevention of UTI to keep the status or to reduce the prevalence more.