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Now showing items 1-20 of 22

APPROPRIATENESS, OUTCOMES OF ANTIMICROBIAL TREATMENTS AND ASSOCIATED FACTORS AMONG PATIENTS WITH PNEUMONIA IN MEDICAL AND PEDIATRIC WARDS OF PUBLIC HOSPITALS IN HARAR, EASTERN ETHIOPIA: A RETROSPECTIVE CHART REVIEW

Jambo, Abera; Edessa, (AssisProf) Dumessa; Gashaw, (Assis Prof) Tigist (Haramaya university, 2021-10)

Pneumonia is the leading cause of morbidity and mortality among all age groups throughout the world, especially in low and middle-income countries. The empiric approach of treating hospitalized patients with pneumonia ...
PATTERN OF EPILEPSY TREATMENT OUTCOME AND ITS PREDICTORS AMONG EPILEPTIC PATIENTS ON FOLLOW UP AT NEUROLOGIC CLINIC OF HIWOT FANA SPECIALIZED UNIVERSITY HOSPITAL AND DILCHORA REFERAL HOSPITAL, EASTERN ETHIOPIA: A RETROSPECTIVE COHORT STUDY

Siraj, Ammas; Minsamo, (Assis Prof) Kirubel; Bekele, (PhD) Tadesse (Haramaya university, 2021-10)

Epilepsy is a chronic neurological disease with variable therapeutic responses. To design effective treatment strategies for epilepsy, it is important to understand treatment responses and predictive factors. However, ...
IN-HOSPITAL MORTALITY AND ITS ASSOCIATED FACTORS AMONG ADULT ACUTE HEART FAILURE PATIENTS AT HARAMAYA UNIVERSITY HIWOT FANA COMPREHENSIVE SPECIALIZED HOSPITAL, HARAR, ETHIOPIA

Deriba, Chala; (Assistant Professor) Amare, Firehiwot; Abdela, Jemal (Assistant Professor) (Haramaya university, 2021-10)

Acute heart failure is the gradual or rapid change of heart failure signs and symptoms, which poses a unique diagnostic and management challenge, requiring urgent therapy. It is responsible for nearly one million ...
Chemotherapy Medication Error and Associated Factors among Cancer Patients Attending Ambulatory Unit of Oncology Ward at Haramaya University Hiwot-Fana Comprehensive Specialized Hospital, Harar, Eastern Ethiopia

Neim Bedewi; (Assis Prof) Kirubel Minsamo; (Assist Prof) Bisrat Hagos (Haramaya University, 2023-10)

Cancer patients are at a high risk to encounter Medication errors partly due to the inherent toxicity and narrow therapeutic index of anti-cancer medications. Thus, assessing the occurrence of chemotherapy medication ...
TREATMENT OUTCOMES AND ASSOCIATED FACTORS AMONG PATIENTS ADMITTED WITH VENOUS THROMBOEMBOLISM AT PUBLIC HOSPITALS OF HARAR TOWN, EASTERN ETHIOPIA: A CROSS-SECTIONAL STUDY.

Dawit Abraham; (AssistProfe) Kirubel Minsamo; (Ass. Profes) Tigist Gashaw; (Ass. Profe) Shambel Nigussie (Haramaya University, 2023-10)

Venous thromboembolism is the third most common cause of cardiovascular death and is responsible for more than 3 million deaths annually worldwide. Despite high rates of morbidity and mortality associated with VTE, ...
ANTIBIOTIC KNOWLEDGE, PRACTICE, AND ASSOCIATED FACTORS IN THE TREATMENT OF ACUTE UPPER RESPIRATORY TRACT INFECTIONS FOR CHILDREN AMONG CAREGIVERS AT HARARI REGION HEALTH FACILITIES

Chala Abrahim; Mr. Dumessa Edessa; Mr. Jemal Abdela (Haramaya University, 2023-10)

Background: Acute upper respiratory tract infections are infections caused by viruses or bacteria, and most of the time they are self-limited and treated without the consumption of antibiotics. Due to inadequate knowledge ...
IN-HOSPITAL MORTALITY AND ITS ASSOCIATED FACTORS AMONG HOSPITALIZED STROKE PATIENTS IN HARAR PUBLIC HOSPITALS, EASTERN ETHIOPIA

Ziyad Abas Hassen; Dumessa Edessa; Tigist Gashaw (Haramaya University, 2023-10)

Background: Stroke is rapidly developing clinical signs of focal or global disturbance of cerebral function, with symptoms lasting more than 24 hours and leading to death, with no apparent cause other than a pathological ...
CHEMOTHERAPY MEDICATION ERROR AND ASSOCIATED FACTORS AMONG CANCER PATIENTS ATTENDING AMBULATORY UNIT OF ONCOLOGY WARD AT HARAMAYA UNIVERSITY HIWOT-FANA COMPREHENSIVE SPECIALIZED HOSPITAL, HARAR, EASTERN ETHIOPIA

Neim Bedewi; (Assis Profe) Kirubel Minsamo; (Assis Prof) Bisrat Hagos (Haramaya University, 2023-10)

Cancer patients are at a high risk to encounter Medication errors partly due to the inherent toxicity and narrow therapeutic index of anti-cancer medications. Thus, assessing the occurrence of chemotherapy medication ...
EVALUATION OF WOUND HEALING AND ANTIBACTERIAL ACTIVITIES OF 80% METHANOL CRUDE EXTRACT OF THE LEAVES OF EHRETIA CYMOSA THONN (BORAGINACEAE) IN MICE MODEL

Eshetu Mekonnen; (Assis Prof )Tigist Gashaw; (Assis Prof)Dumessa Edessa (Haramaya University, 2024-09)

Ehretia cymosa is one of the medicinal plants used traditionally for the treatment of wounds and a range of ailments including fever, gastric ulcer, dysentery, and toothache. However, the scientific evidence justifying ...
MAGNITUDE OF DRUG THERAPY PROBLEM AND ASSOCIATED FACTORS AMONG ADULT PATIENTS ADMITTED TO SURGICAL WARD OF WACHEMO UNIVERSITY COMPREHENSIVE SPECIALI ZED HOSPITAL, HOSSANA, CENTRAL ETHIOPIA.

Taju Seid; (Assis Profe) Shambel Nigussie (Haramaya University, 2024-09)

Drug therapy problems are common in hospitalized patients and may lead to increased hospital stays, health care costs, and increased risk of morbidity and mortality. Surgical patients inherently have operative interventions, ...
EVALUATION OF WOUND HEALING AND ANTIBACTERIAL ACTIVITIES OF 80% METHANOL CRUDE EXTRACT OF THE LEAVES OF EHRETIA CYMOSA THONN (BORAGINACEAE) IN MICE MODEL

Eshetu Mekonnen; (Assis Prof) Tigist Gashaw; (Assis Prof) Dumessa Edessa (Haramaya University, 2024-11)

Ehretia cymosa is one of the medicinal plants used traditionally for the treatment of wounds and a range of ailments including fever, gastric ulcer, dysentery, and toothache. However, the scientific evidence justifying ...
EVALUATION OF IN-VIVO WOUND HEALING ACTIVITIES IN MICE MODELS AND IN-VITRO ANTI-OXIDANT ACTIVITIES OF RICINUS COMMUNIS L. SEED SOLVENT/CRUDE EXTRACTS.

DESALEGN DANSA (B. Pharm); TADESSE BEKELE (PhD); ABRAHAM NIGUSSIE (PhD) (Haramaya University Harar, 2024-11)

Background:Ricinus communis (R.communis) is one of the traditional medicinal plants used in Ethiopia to treat wounds and other diseases. However, the plant has not been scientifically validated to treat wounds. Objective ...
ANTI-DIABETIC ACTIVITIES OF 80% METHANOL EXTRACT AND SOLVENT FRACTIONS OF CROTON MACROSTACHYUS HOCHST. EX DELILE (EUPHORBIACEAE)

Nahom Samuel (B.pharm); Dr. Tadesse Bekele (PhD); Dr. Abraham Nigussie (PhD) (Haramaya University Harar, 2024-11)

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by high blood sugar levels. Managing DM has been challenging due to limited treatment options, high costs, and potential side effects of ...
TREATMENT OUTCOME OF ACUTE KIDNEY INJURY AND ASSOCIATED FACTORS AMONG PATIENTS ADMITTED IN THE INTENSIVE CARE UNIT OF HIWOT FANA COMPREHENSIVE SPECIALIZED HOSPITAL, HARAR, EASTERN ETHIOPIA.

MENBERE DEBELE; Mr. Shambel Nigussie (MSc, Assistant Professor); Mrs. Tigist Gashaw (MSc, Assistant Professor) (HARAMAYA UNIVERSITY, 2025-08)

Background: The incidence of acute kidney injury (AKI) in intensive care units has risen over the past decade, affecting an estimated 13 million people annually and leading to 1.7 million deaths worldwide. Despite its ...
IN VITRO ANTIBACTERIAL EVALUATION OF CRUDE EXTRACT AND SOLVENT FRACTIONS OF CLERODENDRUM MYRICOIDES AND KALANCHOE DENSIFLORA AGAINST SELECTED BACTERIAL ISOLATES CAUSING BOVINE MASTITIS.

BALISA YUSUF; Jemal Abdela (B. Pharm, MSc, Assist. Professor); Tewodros Tesfa (BSc. Pharm, MSc. Assist. Professor) (HARAMAYA UNIVERSITY, 2025-09)

Background: Mastitis is a bacterial disease with estimated annual costs of 35 billion USD in the global dairy industry. Although antibiotics are the remedies in mastitis treatment, their effectiveness is lost because ...
POTENTIALLY INAPPROPRIATE MEDICATION USE AND ASSOCIATED FACTORS AMONG GERIATRIC PATIENTS HOSPITALIZED WITH CARDIOMETABOLIC DISORDERS IN PUBLIC HOSPITALS OF EASTERN ETHIOPIA; A MULTI-CENTER PROSPECTIVE OBSERVATIONAL STUDY

HAMZA ABDUREMAN (B. PHARM); Kirubel Minsamo (MSc, Assistant professor); Abraham Nigussie (PhD, Assistant professor) (HARAMAYA UNIVERSITY, 2025-09)

Background: Potentially inappropriate medications (PIMs) are drugs where the risks of taking them are more than the benefits or where safer alternatives exist. Among geriatric patients with cardiometabolic conditions, ...
ANTIBIOTIC KNOWLEDGE, PRACTICE, AND ASSOCIATED FACTORS AMONG MOTHERS OF CHILDREN UNDER-FIVE IN RURAL HARAMAYA DISTRICT, EASTERN ETHIOPIA

JABIR ALIYE (B.PHARM); Mr.Kirubel Minsamo (MSc, Assistant Professor of Clinical Pharmacy); Dr.Abraham Nigussie (PhD) (Haramaya University, 2025-09)

Background: Lack of knowledge among mothers regarding antibiotic use in children under five contributes to inappropriate use, a key driver of antimicrobial resistance (AMR). Despite their critical role, limited data ...
TREATMENT OUTCOME OF MENINGITIS AND ITS ASSOCIATED FACTORS AMONG NEONATES ADMITTED IN PUBLIC HOSPITALS AT HARAR TOWN, EASTERN ETHIOPIA

GETAHUN TAMIRU; Mr. Shambel Nigussie (PhD Fellow); Dr. Tadesse Bekele (Ph.D. in Medicinal Chemistry) (HARAMAYA UNIVERSITY, 2025-10)

Background: Meningitis in neonates significantly burdens public health in low- and middle income countries. However, data on treatment outcomes and factors contributing to poor prognosis are scarce. This study aimed to ...
MORTALITY AND ITS ASSOCIATED FACTORS AMONG COLORECTAL CANCER PATIENTS ON CHEMOTHERAPY FOLLOW UP AT HIWOT FANA COMPREHENSIVE SPECIALIZED HOSPITAL AND DILCHORA GENERAL HOSPITAL, EASTERN ETHIOPIA

Ibrahim Ismael (B. Pharm); Dr. Dumessa Edessa (Ph.D); Mr. Jemal Abdela (MSc, Assistant Professor of Pharmacology) (Haramaya University,, 2025-11)

Background: Colorectal cancer is the third most commonly diagnosed cancer and the second biggest cause of cancer-related deaths worldwide, impacting both developed and developing nations. The present research aimed to ...
INCIDENCE OF HOOSPITAL ACQUIRED INFECTION, TREATMENT OUTCOMES AND FACTORS ASSOCIATED WITH POOR TREATMENT OUTCOMES AMONG ADULT INPATIENTS WITH HOSPITAL ACQUIERD INFECTION AT HIWOT FANA COMPREHENSIVE SPECIALIZED UNIVERSITY HOSPITAL, EASTERN ETHIOPIA PROSPECTIVE LONGTUDNAL STUDY

FEDILA SHUKRALA; Mr. Kirubel Minsamo (B.Pharm, MSc, Assistant Professor).; Mr. Jemal Abdela (B. Pharm, MSc, Assistant Professor) (HARAMAYA UNIVERSITY, 2025-12)

Background: Hospital-acquired infections are among the most common adverse events in healthcare, causing substantial morbidity, mortality, and financial burden worldwide. These infections are often associated with ...

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