MAGNITUDE OF TRANSFUSION-TRANSMITTED INFECTIONS AND ASSOCIATED FACTORS AMONG BLOOD DONORS AT NEKEMTE BLOOD BANK, WESTERN ETHIOPIA

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dc.contributor.author kiflu, Abdi
dc.contributor.author mitiku, Habtamu Major Advisor Mr.
dc.contributor.author weldegebreal, Fitsum Co Advisor Mr.
dc.date.accessioned 2018-01-29T13:18:58Z
dc.date.available 2018-01-29T13:18:58Z
dc.date.issued 2018-05
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/2967
dc.description 68 en_US
dc.description.abstract Background: Globally, more than 112.5 million units of blood are collected every year from the voluntary unpaid, family, replacement and paid donors which save millions of lives each year. Each transfusion might have risk of transfusion transmissible blood-borne pathogens like Human Immuno Deficiency Virus, Hepatitis C Virus, Hepatitis B Virus and syphilis. However, there is limited information with regard to the burden of major transfusion-transmitted infections and their associated factors in study area. Objective: The aim of this study was to determine the magnitude of transfusion-transmissible infections and associated factor among blood donors at Nekemte blood bank, Western Ethiopia from February 10th to March 10th 2018. Method: A cross sectional study was conducted among 280 blood donors, at Nekemte blood bank Service. Socio demographic factor, behavioral factors and clinical factors about the donors were obtained by interview using a structured questionnaire. The blood was tested for HIV, HCV, HBV and syphilis using enzyme linked immune sorbent assay method and participant data were analyzed using the Program for Social Science version 20. Bivariate and multivariate Logistic regression analysis was used to analyses the data and identify the association. Result: The overall magnitude of transfusion transmitted infection in this study was 7.1% (20/280). The sero prevalence of HBV, HCV and syphilis was 3.9% (11), 1.4% (4) and 1.8 % (5) respectively while HIV was not detected and also no co infection. Age 25-34 years (AOR = 4.993; 95%CI: 1.400, 17.807), those who drink alcohol (AOR = 4.059; 95%CI: 1.254-13.138) and had multiple sexual partners (AOR= 4.938; 95%CI 1.466-16.631) found associated with transfusion transmitted infections Conclusion: The present study shows similar magnitude of transfusion transmitted infections (TTIs) compared to the recent study done in Ethiopia. The predominant TTI magnitude seen in this study was HBV. In this study age group 25-34, alcohol consumption and multiple sexual partners were among factors associated to transfusion transmitted infections. Health information dissemination and creating awareness for blood donors how to prevent transmission of TTI is very important. en_US
dc.description.sponsorship Haramaya university en_US
dc.language.iso en_US en_US
dc.publisher Haramaya university en_US
dc.subject transfusion transmitted infection, HIV, HCV, HBV, syphilis en_US
dc.title MAGNITUDE OF TRANSFUSION-TRANSMITTED INFECTIONS AND ASSOCIATED FACTORS AMONG BLOOD DONORS AT NEKEMTE BLOOD BANK, WESTERN ETHIOPIA en_US
dc.type Thesis en_US


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