Abstract:
ABSTRACT
Background. Infantile hypertrophic pyloric stenosis is an anomaly whose etiology is not
clear, but It is characterized by progressive hypertrophy of the circular muscles of the
pylorus with consequent obstruction of the gastric outflow, mostly in neonates and
infants under the age of 1 year. the visible gap of prolonged duration of illness, prolonged
preoperative hospital stay and high proportion of dehydration and electrolyte disturbance,
in patients with Infantile Hypertrophic Pyloric Stenosis, motivated me to make this study
at Hiwot Fana Specialized University Hospital and Jigjiga University Sheik Hassen
Yabare Referral Hospital.
Objectives: -To assess the Treatment outcome and associate factors of infantile pyloric
sphincter stenosis among pediatric patients admitted to HFCSUH and JUSHYRH for the
last 3 years from January 1,2020 to December 31,2022. Data was collected from
(November, 1 to 31,2022)
Methodology: The study was conducted on cases of infantile hypertrophic pyloric
stenosis admitted to HFCSH and JUSHYRH from January, 2020- December, 2022. The
study design was a cross sectional with sample size of 78. Bivariate analysis and Multivariate logistic regression was employed to assess the treatment outcome and associating
factors of infantile hypertrophic pyloric stenosis. The significance of association between
dependent and independent variables was declared by using odds ratio with 95%
confidence interval and P value <0.05.
Results:A total of 78 IHPS patients were admitted and operated during the period of study.
Among these, 8 were excluded from the study due to incomplete data. Out of 70 patients, 56
(80 %) were males and 14 (20 %) females with a male to female ratio of 4:1.
The duration of symptoms before admission ranged from 2 to 60 days (median 20 days). The
most common symptoms reported were non-bilious vomiting (100%) and poor weight gain
61.4%). Majority (78.6%) of our patients had electrolyte imbalance. Potassium imbalance was the
most common among the patients seen. The diagnosis of IHPS was made by ultrasound. The
treatment was Ramstedt’s pyloromyotomy in all cases.
Conclusion:This study has demonstrated that infantile pyloric stenosis is 4 times more common
in males compared to females and is more common among first born neonates compared to
higher order neonates.Delayed presentation, prolonged preoperativehospital stay, surgical site
infection and high proportion of dehydration and electrolyte disturbance were the main predictors
of poor outcome.
