SEROPREVALENCE OF HEPATITIS B VIRUS AND ASSOCIATED FACTOR AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE IN JIGJIGA TOWN PUBLIC HEALTH FACILITIES, EASTERN ETHIOPIA

Abstract

Background: -Hepatitis B Virus is one of major a global health threat affecting millions of people yearly by causing morbidity and mortality. The risk of developing chronic Hepatitis B virus is different across the age in which 95% of infections acquired during the perinatal period. Despite the challenge of hepatitis B virus there are limited study done in Jigjiga town. Therefore, this study will provide important data regarding seroprevalence of the hepatitis B virus and associated factors among pregnant women attending antenatal care of Jigjiga town public health facilities. Objectives The aim of this study wasto determine seroprevalence of Hepatitis virus and associated factor among pregnant women attending antenatal care in Jigjiga town public health facilities from to March 4 to April 4, 2019. Methodology: A cross-sectional study was used among pregnant women attending the antenatal clinic. Using systematic sampling 589 pregnant women were enrolled in the study. Data on socio demographic and Hepatitis B virus associated factors collected using a standard questionnaire. Five milliliter of venous blood samples were collected and tested for Hepatitis B using Enzyme Linked Immunosorbent assay diagnostic method. Finally, the data were entered using Epidata version 3.1 and export to SPSS version 20 for analysis. Logistic regression analysis used to identify independent predictors of the outcome and a P value < 0.05 was considered statistically significant. Result This study indicated that 8.5% (95% CI 6.5-10.7).) of the study participants were seropositive for HBsAg. Having any surgical history [AOR 3.41, 95%CI (1.26-9.24)], Family history of hepatitis B [AOR 4.96, 95% CI (2.11-10.60)], history of Shared sharp materials [AOR 2.78 95% CI (1.13-6.83] and having multiple sexual partners [AOR 6.12,95% (2.12-17.64)] were significant predictors of HBV infection. Conclusion: According to the research finding seroprevalence of HBV was high in Jigjiga town public Health facilities. The finding indicates that history of surgery, family history with hepatitis, sharp sharing and multiple sexual partners were significantly associated with hepatitis B infection Seropositivity in Jigjiga. Therefore, health information dissemination on mode of transmission of this Virus and further investigation on the population based study should be conducted.