Abstract:
Background: Tuberculosis is a major public health problem in many parts of the world.
Nearly one-third of the world’s population is infected with tubercle bacilli and hence at
risk of developing active disease. Treatment success remains low, at 55% globally
because of low compliance and other associating factors. Ethiopia stands at the ninth
place in the global rank by the estimated number of cases. In Ethiopia, multiple drug
resistance prevalence is about 2.3% among new tuberculosis cases and 17.8% among
previously treated cases.
Objective: The objective of this study was to assess facility based compliance and
factors associated with tuberculosis treatment among adult clients in facilities in the
Harari regional state, Eastern Ethiopia, March 1 to April 20, 2019.
Methods: A facility based cross-sectional quantitative survey conducted. A total of 428
tuberculosis clients on therapy were included by convenient sample technique. All
health facilities providing Directly observed Treatment short course services in the
region were included in sampling. Data entered to epidata version 3.1 and exported to
SPSS version 21 for analysis. Associations among selected factors with compliance
identified by adjusted odds ratios and with their 95% confidence intervals from crude
odds ratio with p < 0.25 variables was considered the significance point to be at P <
0.05.
Result: Compliance among the respondents was 87.7% (320 respondents).Those clients
who had supporter 4.58 times higher (AOR: 4.58, 95% CI: 1.74-12.08), distance from
the facility were 6.6 times higher (AOR; 6.60, 95% CI 2.51-17.37), knowledge of
seriousness of TB (AOR: 3.36, 95% CI: 1.20-9.39) and knowledge of daily dose (AOR:
3.31, 95% CI: 1.01-10.88) were associated with high compliance.
Conclusion: The magnitude of compliance in the study area was 87.7%. General patient
compliance to TB treatment in Harari region is associated with supporter during
medication taking, having knowledge of prescribed dose, patient knowledge of TB disease
and shorter distance from the facility
