Abstract:
Urinary tract infection is one of the most common infections worldwide. It has been reported
to be around two to four times higher in diabetics compared to non-diabetic patients. The
prevalence urinary tract infection among diabetes mellitus varies from place to place.
However, the problem was not studied in western Ethiopia Ilubabor Zone. Therefore, this
study was aimed to determine the magnitude of bacterial uropathogens, associated factors and
antimicrobial susceptibility pattern among adult diabetic patient attending at Matu Karl Henze
Referral Hospital, Ilubabor Zone, western Ethiopia from February to March, 2018. A cross
sectional study was conducted among 233 consecutively selected adult diabetic patients. A
structured questionnaire was used to collect data. Mid-stream urine specimen was collected
and examined for the presence of bacteria by using culture, microscopy and biochemical
analysis. Modified Kerby Buer disc diffusion method was used for the determination of
antimicrobial susceptibility. Data were analyzed using SPSS version 22. The overall
prevalence of urobacteia was 16.7% (16/233). The predominant isolates were E.coli 25.6%
followed by Klebsiellaspp (20.5%). Being female (AOR: 3.56; 95%CI: 1.44, 8.76), previous
history of urinary tract infection (AOR: 2.31; 95% CI: 1.09, 4.90) and no formal education
(AOR: 2.55; 95% CI: 1.19, 5.49) were significantly associated with urinary tract infections
(p<0.05). Amoxicillin-clavulanic acid (92%) and Ceftriaxone (84%) showed higher sensitivity
against Gram positive and negative, respectively. However, all isolates were resistant to
penicillin G (100%). More than 87% of the isolates were multidrug resistant. The overall
prevalence of urinary tract infection was showed urinary tract infection still problem. Those
female in gender, previous history of urinary tract infection and no formal education
weremore likely to be infected with bacterial uropathogens. Bacterial uropathogen isolates
showed varying degrees of sensitivity and resistance to most antimicrobial agents tested.
Mostof the bacterial isolates were multidrug resistant. Therefore, health information
dissemination about urinary tract infection prevention and appropriate antibiotic use should be
given. Antimicrobial treatment for urinary tract infection in diabetic patients should be
supported with periodic culture and drug susceptibility test.
