MAGNITUDE OF BACTERIAL UROPATHOGENS, ASSOCIATED FACTORS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN AMONG ADULT DIABETIC PATIENT ATTENDING AT MATU KARL HENZE REFERRAL HOSPITAL, SOUTH-WEST ETHIOPIA

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dc.contributor.author gutema, Tesfaye
dc.contributor.author teklemariam, Zelalem Major Advisor Mr
dc.contributor.author weldegebreal, Fitsum Co Advisor Mr.
dc.date.accessioned 2018-01-28T19:24:44Z
dc.date.available 2018-01-28T19:24:44Z
dc.date.issued 2018-05
dc.identifier.uri http://localhost:8080/xmlui/handle/123456789/3236
dc.description 97 en_US
dc.description.abstract Urinary tract infection is one of the most common infections worldwide. It has been reported to be around two to four times higher in diabetics compared to non-diabetic patients. The prevalence urinary tract infection among diabetes mellitus varies from place to place. However, the problem was not studied in western Ethiopia Ilubabor Zone. Therefore, this study was aimed to determine the magnitude of bacterial uropathogens, associated factors and antimicrobial susceptibility pattern among adult diabetic patient attending at Matu Karl Henze Referral Hospital, Ilubabor Zone, western Ethiopia from February to March, 2018. A cross sectional study was conducted among 233 consecutively selected adult diabetic patients. A structured questionnaire was used to collect data. Mid-stream urine specimen was collected and examined for the presence of bacteria by using culture, microscopy and biochemical analysis. Modified Kerby Buer disc diffusion method was used for the determination of antimicrobial susceptibility. Data were analyzed using SPSS version 22. The overall prevalence of urobacteia was 16.7% (16/233). The predominant isolates were E.coli 25.6% followed by Klebsiellaspp (20.5%). Being female (AOR: 3.56; 95%CI: 1.44, 8.76), previous history of urinary tract infection (AOR: 2.31; 95% CI: 1.09, 4.90) and no formal education (AOR: 2.55; 95% CI: 1.19, 5.49) were significantly associated with urinary tract infections (p<0.05). Amoxicillin-clavulanic acid (92%) and Ceftriaxone (84%) showed higher sensitivity against Gram positive and negative, respectively. However, all isolates were resistant to penicillin G (100%). More than 87% of the isolates were multidrug resistant. The overall prevalence of urinary tract infection was showed urinary tract infection still problem. Those female in gender, previous history of urinary tract infection and no formal education weremore likely to be infected with bacterial uropathogens. Bacterial uropathogen isolates showed varying degrees of sensitivity and resistance to most antimicrobial agents tested. Mostof the bacterial isolates were multidrug resistant. Therefore, health information dissemination about urinary tract infection prevention and appropriate antibiotic use should be given. Antimicrobial treatment for urinary tract infection in diabetic patients should be supported with periodic culture and drug susceptibility test. en_US
dc.description.sponsorship Haramaya university en_US
dc.language.iso en_US en_US
dc.publisher Haramaya university en_US
dc.subject Magnitude; associated factors; urinary tract infections; bacterial uropathogens; antimicrobial susceptibility; Ilubabor, south west Ethiopia. en_US
dc.title MAGNITUDE OF BACTERIAL UROPATHOGENS, ASSOCIATED FACTORS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN AMONG ADULT DIABETIC PATIENT ATTENDING AT MATU KARL HENZE REFERRAL HOSPITAL, SOUTH-WEST ETHIOPIA en_US
dc.type Thesis en_US


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