TREATMENT OUTCOME OF TUBERCULOSIS CASES BY HIV STATUS AND ITS ASSOCIATED FACTORS IN HARAMAYA GENERAL HOSPITAL, OROMIA, ETHIOPIA

Abstract

Background: Tuberculosis (TB) is the second leading cause of death from a single infectious agent, and leading cause of death among people living with human immunodeficiency virus worldwide. Tuberculosis and Human immunodeficiency virus co-infection is a key problem to the global target set to end tuberculosis. Objective: The aim of this study was to assess the treatment outcome of tuberculosis cases by HIV status and its associated factors in Haramaya General Hospital, Oromia, Ethiopia, from November 15 to December 30, 2022. Methods: A cross-sectional study was done. The standard tuberculosis registry and treatment cards of patients who received anti-tuberculosis treatment in the hospital from September 2017 to August 2022 were reviewed. The data collected using a structured data extraction format were entered to Epi 7 package software and analyzed using Statistical Package for the Social Sciences software version 21. Results: Out of the 420 samples addressed, 91.0% of all TB patients had successful treatment outcome. Treatment success rate of HIV positive TB patients and HIV negative TB patients were 80.0% and 91.9%, respectively. Being HIV negative (AOR: 2.561, 95% CI: 1.002-6.542), being in age group of 20-35 years (AOR: 2.950, 95% CI: 1.171-7.431), and urban residence (AOR: 2.961, 95% CI: 1.466-5.981) were associated with the TB treatment success rate. Conclusion: There is high treatment success rate among all TB patients. HIV status influenced TB treatment outcome. Providing effective treatment supervision and patient and care giver’s education, and earlier initiation of isoniazid preventive therapy recommended for reducing HIV co-infection among tuberculosis and improving TB success rate.